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1.1 State the research question the authors plan to answer. [4 marks]
1.2 Identify the type of study design used in this study. [2 marks]
1.3 What was the source population and the study population for this research trial? How were the study population recruited? [3 mark]
1.4 Identify the inclusion and exclusion criteria applied to the study population. [2 marks]
1.5 Identify the interventions given to the people in the treatment group and the control group. [3 marks]
1.6 Identify the primary outcome/s or dependent variable/s for this study. [2 marks]
The next 3 questions ask you to briefly list the characteristics, and provide some examples, if relevant, you would consider when appraising a research study, such as Kravlikova et al 2009.
Question 1.7 focuses on how to determine if the study is relevant or generalisable (or externally valid) to your clinical practice, or, your research question.
1.7 What characteristics of the study do you consider to determine if it is generalisable? [8 marks]
1.8 What characteristics of this type of study design will you consider to determine if its findings are valid? [8 marks]
1.9 What characteristics of the findings of this type of study design will you consider to determine their magnitude and significance (clinical and statistical)?
2.1 Was the assignment of participants to groups randomised? [1 mark]
2.2 Was the allocation sequence concealed? [1 mark]
2.3 Were the groups similar at baseline or the start of the trial?
2.3 Were the groups similar at baseline or the start of the trial? [3 marks]
2.4 Were participants blind to which study group they were in? [1 mark]
2.5 Were the assessors of the outcome/s measured blind to the participants study group?
[2 marks]
2.6Were the outcomes measured reliable?
[1 mark]
2.7 Were all participants who entered the research study properly accounted for at the study conclusion, and how complete was the follow-up?
2.8 What is intention to treat analysis? [1 mark]
2.9 Was intention to treat analysis used? [1 mark]
2.10Did the study have enough participants to minimise the play of chance?
3.1 Experimental Event Rate (EER) for
3.3Relative Risk (RR) of
3.4 Is this a rate ratio or risk ratio? [1 mark]
3.5 Absolute Risk Difference [2 marks]
3.6 Number Needed to Treat [2 marks]
3.7Describe the NNT in words
4.1 What are the main research question/s of this study? [4 marks]
4.2 Was there a representative and well-defined sample? [3 marks]
4.3 Detail the participants and their diabetic foot ulcers (main characteristics, inclusion and exclusion criteria.)
4.4 What was the exposure? Was the exposure determined accurately? [2 marks]
4.5 What were the outcomes? Were the outcomes measured accurately? [3 marks]
4.6 Was the follow-up of participants sufficiently long and complete? [4 marks]
4.7 What prognostic factors were considered? [5 marks]
4.8Describe the main results and conclusions of this paper
4.8 Describe the main results and conclusions of this paper [6 marks]
[3 mark]
[4 marks]
[2 marks]
[1 mark]
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